Increased blood creatinine concentration, eGFR and renal function tests

The principal renal function tests are plasma creatinine concentration, estimated glomerular filtration rate (eGFR) calculated from the creatinine concentration result and urinalysis. Impaired filtration rate with or without proteinuria and/or haematuria is suggestive of renal disease. If eGFR is over 60 ml/minute, no further investigations or follow-up are needed, unless other signs suggestive of renal disease are present (haematuria, proteinuria, microalbuminuria in a diabetic patient).